MRNA Unusual Options: $7.8M Massive Call Selling - Sep 5,2025
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π MRNA: Whales Just Dumped $7.8 MILLION in Call Options - Pipeline Catalysts Can't Save This Sinking Ship!
π September 5, 2025 | π₯ Extreme Unusual Activity Detected
π― The Quick Take
Someone just UNLOADED $7.8 MILLION worth of MRNA call options in a massive institutional sell-off! π This isn't your average profit-taking - this is an 8/10 EXTREME unusual score, hitting 869x larger than average MRNA option trades! With the stock down 40% YTD and trading at $25.31, these whales are running for the exits despite multiple pipeline catalysts ahead. Translation: Big money thinks MRNA's troubles are far from over! π°
π° The Option Flow Breakdown
π What Just Happened
Let me break down this institutional massacre that hit the tape this afternoon:
| Time | Symbol | Side | Type | Strike | Expiration | Premium | Volume | OI | Size | Spot Price | Option Price |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 13:47:01 | MRNA20250912C26 | SELL | CALL | $26 | 2025-09-12 | $1M | 21K | 11K | 20,000 | $25.16 | $0.52 |
| 13:17:47 | MRNA20250919C25 | SELL | CALL | $25 | 2025-09-19 | $1.9M | 28K | 16K | 13,603 | $25.1 | $1.39 |
| 12:38:40 | MRNA20250919C25 | SELL | CALL | $25 | 2025-09-19 | $1.8M | 14K | 16K | 13,603 | $24.97 | $1.35 |
| 13:47:01 | MRNA20250912C27.5 | SELL | CALL | $27.5 | 2025-09-12 | $220K | 10K | 66 | 10,000 | $25.16 | $0.22 |
| 13:47:01 | MRNA20250912C24.5 | BUY | CALL | $24.5 | 2025-09-12 | $1.2M | 10K | 10K | 10,000 | $25.16 | $1.22 |
Total Premium Flow: $7.8M (80% SELLING!)
π€ What This Actually Means
Real talk: This trade scored an 8/10 EXTREME unusual score - that's "holy crap, what do they know?" territory! π
Here's the translation for us regular folks:
The Massive Sell Orders (Bearish AF): - $4.7M in September 19th calls DUMPED - That's next Friday! - Selling the $25 strike when stock is at $25.31 - Volume absolutely CRUSHING open interest (28K vs 16K) - These aren't hedges - this is straight-up capitulation!
The Lone Buy Order (Dead Cat Bounce Play?): - $1.2M buying September 12th $24.50 calls - Ultra short-term (expires in 7 days!) - Probably a volatility play or hedging the massive sells
The Numbers That Matter: - Unusualness: 869x larger than average MRNA option trade! - Percentile: 99.99% - literally off the charts - Days Between Similar Trades: Only happens every 2.1 days (when it's bad news!)
Translation: Institutional money is FLEEING MRNA like it's on fire! When someone dumps $7.8M in options with the stock already down 40% YTD, they're not playing games - they think it's going lower! π
π Technical Setup / Chart Check-Up

Looking at the YTD performance, MRNA is in absolute freefall:
Key Metrics: - π YTD Return: -39.74% (OUCH!) - π Current Price: $25.31 - π Start of Year: $42.00 - π΄ Max Drawdown: -50.24% (hit in April) - π₯ Volatility: 5.07
Technical Levels: - π° Current: $25.31 - π Strike Being Dumped: $25-$27.50 (right at current levels!) - π‘οΈ 52-Week Low: ~$20 (only 20% below!) - π Year High: $42 (would need 66% rally to recover)
Translation: MRNA has been bleeding out all year, and these whales think the pain isn't over! The stock is stuck in a death spiral, down 40% YTD with no floor in sight! π’
πͺ Catalysts
Upcoming Events
π§ͺ Phase 3 Cancer Vaccine Data - Late 2025 - mRNA-4157/V940 with Merck's Keytruda - Three pivotal trials: melanoma, lung cancer, skin cancer - Could unlock $10+ billion market opportunity
π RSV Vaccine Expansion - Recently Approved - Expanded to adults 18-59 at risk - 83.7% efficacy demonstrated - Competing with Pfizer and GSK
π¦ CMV Vaccine Phase 3 - Ongoing - CMVictory trial in women of childbearing age - No licensed CMV vaccine exists - Addresses major unmet medical need
Past Events (Already Happened)
π Q2 2025 Earnings Disaster - August 1 - Revenue crashed 41% to $142M - Net loss of $825M ($2.13 per share) - 10% workforce reduction announced
β Flu Vaccine Success - June 30 - 26.6% better than standard flu vaccines - Positive Phase 3 data across all strains - Paves way for combo flu/COVID shots
π² Price Targets & Probabilities
Based on the massive institutional selling and deteriorating fundamentals:
π° Bear Case (60% chance)
Target: $18-$22 by year-end - Pipeline delays or failures likely - Cash burn continues at unsustainable rate - Competition crushes respiratory vaccine market share - Those September calls expire worthless!
π Base Case (30% chance)
Target: $23-$27 - Stock chops sideways in this range - Minor pipeline progress offsets cash burn - Respiratory vaccines gain some traction - Whales who sold calls keep their premium
π Bull Case (10% chance)
Target: $30-$35 - Cancer vaccine data surprises positively - Multiple pipeline successes announced - Partnership or acquisition rumors emerge - These call sellers get burned (unlikely!)
π‘ Trading Ideas
π‘οΈ Conservative Play: "Premium Vulture"
- Strategy: Sell $20 puts, 30-45 days out
- Premium: ~$0.50-$0.75 per contract
- Why it works: Collect premium with 20% downside cushion
- Risk: Assignment if MRNA crashes below $20
βοΈ Balanced Play: "Follow the Whales"
- Strategy: Buy $25/$20 put spread for October
- Cost: ~$1.50 per spread
- Max profit: $3.50 per spread (233% return)
- Why it works: Profit from continued decline with limited risk
π Aggressive Play: "Catch the Knife"
- Strategy: Buy $27.50 calls for September 19 (contrarian play)
- Cost: ~$0.30-$0.40 per contract
- Why it works: Cheap lottery tickets if shorts cover
- Risk: Total loss likely (these whales are selling for a reason!)
β οΈ Risk Factors
Let's keep it real - here's what could go wrong (or right if you're short):
- Cash Burn Crisis: Operating at $825M quarterly loss with only $7.5B left
- Pipeline Dependency: Everything rides on unproven drugs - one failure could be catastrophic
- COVID Hangover: Revenue down 41% YoY as pandemic boost evaporates
- Competition: Big Pharma crushing them in respiratory vaccines
- Stock Already Destroyed: Down 40% YTD but could go lower!
π― The Bottom Line
Real talk: Someone just made the BIGGEST bearish bet we've seen on MRNA - dumping $7.8 million in calls that's 869x larger than average! This isn't profit-taking, this is EVACUATION! π¨
Here's your action plan:
If you own MRNA: - Consider taking losses and moving on - These whales know something - they're selling hard - Set stop losses immediately below $24
If you're watching: - Stay away until dust settles - Wait for capitulation below $20 for potential bounce - Don't catch falling knives!
If you're bearish: - The whales agree with you! - Consider put spreads for October - $20 looks like next major support
Mark your calendar: September 12th and 19th (option expirations) are going to reveal if these whales were right! π
Remember: When institutions dump $7.8 million in calls on a biotech that's already down 40%, they're not being dramatic - they're being realistic. With Moderna burning cash faster than they can develop drugs, this looks more like the beginning of the end than a buying opportunity! π
β οΈ Options involve risk and are not suitable for all investors. This whale-sized selling is extraordinary and concerning. Biotech stocks can go to zero - never invest more than you can afford to lose. Not financial advice - just showing you why the smart money is running away!